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產品詳情
操作說明
注意事項
Product Information
|
Description |
CX3CR1 rabbit polyclonal |
|
Protein full name |
CX3C chemokine receptor 1 |
|
Synonyms |
Cx3cr1, CX3CR1, CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28, C-X3-C motif chemokine receptor 1 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CX3CR1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
40 kDa |
|
Observed MW. |
40 kDa |
|
Uniprot ID |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
spleen, lung, brain |
Background
CX3C chemokine receptor 1 (CX3CR1) also known as the fractalkine receptor or G-protein coupled receptor 13 (GPR13) is a protein which binds the chemokine CX3CL1 (also called neurotactin or fractalkine). The fractalkine ligand CX3CL1 is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. Expression of this receptor appears to be associated with lymphocytes. CX3CR1 is also expressed by monocytes and plays a major role in the survival of monocytes. Fractalkine signaling has also recently been discovered to play a developmental role in the migration of microglia in the central nervous system to their synaptic targets, where phagocytosis and synaptic refinement occur.
Images
|
Western blot analysis of CX3CR1 (GB11711) at dilution of 1: 1000 Lane 1: HepG2 cell lysate Lane 2: HCT116 cell lysate Lane 3: CaCO2 cell lysate Lane 4: Mouse spleen tissue lysate Lane 5: Mouse lung tissue lysate Lane 6: Mouse brain tissue lysate Lane 7: Rat lung tissue lysate
|
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號合肥國家大學科技園A401室