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Anti -CD8 alpha Rabbit pAb

價格: 在線咨詢
貨號:
DRF101779
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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產(chǎn)品詳情 操作說明 注意事項

Product Information


Description

CD8 alpha rabbit polyclonal

Protein full name

T-cell surface glycoprotein CD8 alpha chain

Synonyms

T-lymphocyte differentiation antigen T8/Leu-2, CD8a, MAL, Leu2, Leu2 T lymphocyte antigen, Ly 35, LYT3, p32, T8 T cell antigen

Immunogen

KLH conjugated Synthetic peptide corresponding to Human CD8 alpha

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membraneSecreted

Uniprot ID

P01732




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human

1: 1500-1: 3000

colon cancer, colon




Background


Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. 




Images


Immunohistochemistry analysis of paraffin-embedded human colon cancer using CD8 alpha (GB12068) at dilution of 1: 3000

Immunohistochemistry analysis of paraffin-embedded human colon using 

CD8 alpha (GB12068) at dilution of 1: 3000

Immunohistochemistry analysis of paraffin-embedded human lung cancer using 

CD8 alpha (GB12068) at dilution of 1: 3000

Immunohistochemistry analysis of paraffin-embedded human tonsil using 

CD8 alpha (GB12068) at dilution of 1: 3000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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