Anti -KDS Rabbit pAb

價(jià)格：在線咨詢

貨號：

KT012272

產(chǎn)品規(guī)格：

100ul

Applications：

IHC/IF

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	KDS rabbit polyclonal antibody
Protein full name	Serine/threonine-protein kinase TAO3
Synonyms	CTCL-associated antigen HD-CL-09, hKFC-A, Dendritic cell-derived protein kinase, DPK, JNK/SAPK-inhibitory kinase, JIK, KDS, Jun kinase-inhibitory kinase, TAOK3, MAP3K18
Immunogen	KLH conjugated Synthetic peptide corresponding to Human KDS
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane, Cytoplasm
Uniprot ID	Q9H2K8

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Human	1: 500-1: 1000	breast cancer, colon cancer

Background

TAOK3 (Serine/threonine-protein kinase TAO3) is also named as DPK, JIK, KDS, MAP3K18 and belongs to the STE Ser/Thr protein kinase family. It acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, it is involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. And this protein can be autophosphorylated.

Images

	Immunohistochemistry of paraffin embedded human breast cancer using TAOK3at dilution of 1:550 (400x lens)
	Immunohistochemistry of paraffin embedded human colon cancer using TAOK3 at dilution of 1:550 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

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