Anti -Mast Cell Chymase Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

DRF101924

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購(gòu)買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	Chymase rabbit polyclonal
Protein full name	Chymase
Synonyms	Alpha-chymase, Mast cell chymase 1, Mast cell chymase 5, mMCP-5, Mast cell protease I, Cma1, Mcpt5
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse Chymase
Isotype	IgG
Purity	Affinity purification
Subcellular location	Secreted

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Mouse, Rat	1: 1000-1: 2000	skin, stomach, uterus
IF	Mouse, Rat	1: 500-1: 1000	skin, stomach, uterus

Background

This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases.

Images

	Immunohistochemistry analysis of paraffin-embedded mouse skin using Chymase (GB111085) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat skin using Chymase (GB111085) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse stomach using Chymase (GB111085) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat stomach using Chymase (GB111085) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat uterus using Chymase (GB111085) at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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