Anti -TCPTP Rabbit pAb

價格：在線咨詢

貨號：

DRF101938

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	TCPTP rabbit polyclonal
Protein full name	Tyrosine-protein phosphatase non-receptor type 2
Synonyms	Protein-tyrosine phosphatase PTP-2, MPTP, Ptpn2, Ptpt
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse TCPTP
Isotype	IgG
Purity	Affinity purification
Predicted MW.	47 kDa
Observed MW.	47 kDa
Uniprot ID	P17706, Q06180

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse	1: 500-1: 1000	ovary

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Three alternatively spliced variants of this gene, which encode isoforms differing at their extreme C-termini, have been described. The different C-termini are thought to determine the substrate specificity, as well as the cellular localization of the isoforms. Two highly related but distinctly processed pseudogenes that localize to distinct chromosomes have been reported.

Images

Western blot analysis of TCPTP (GB111126) at dilution of 1: 1000
Lane 1: Jurkat cell lysate
Lane 2:A549 cell lysate
Lane 3:K562 cell lysate
Lane 4: Mouse ovary tissue lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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