Anti -SHP2 Rabbit pAb

價格：在線咨詢

貨號：

KT011510

產品規(guī)格：

100 μL

Applications：

Species：

H,M,R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產品詳情操作說明注意事項

Product Information

Description	SHP2 rabbit polyclonal antibody
Protein full name	Tyrosine-protein phosphatase non-receptor type 11
Synonyms	Protein-tyrosine phosphatase SYP, SH-PTP2, SHP2, Ptpn11
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse SHP2
Isotype	IgG
Purity	Affinity purification
Predicted MW.	68 kDa
Observed MW.	72 kDa
Uniprot ID	Q06124, P35235, P41499

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	ovary

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.

Images

Picture 1.png

Western blot analysis of PTPN11 (GB111075) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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