Anti -Lipocalin-2 / NGAL Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT011984

產(chǎn)品規(guī)格：

100ul

Applications：

IHC/IF

Species：

品牌：

萬(wàn)物

購(gòu)買(mǎi)數(shù)量：

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產(chǎn)品詳情操作說(shuō)明注意事項(xiàng)

Product Information

Description	NGAL rabbit polyclonal antibody
Protein full name	Neutrophil gelatinase-associated lipocalin
Synonyms	NGAL, Lipocalin-2, Oncogene 24p3, Siderocalin, p25
Immunogen	Recombinant protein corresponding to Human NGAL
Isotype	IgG
Purity	Affinity purification
Subcellular location	Secreted
Uniprot ID	P80188

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Human	1: 500-1: 3000	colon, liver, liver cancer, lung, lung cancer

Background

Lipocalin 2 is a member of the lipocalin family, It involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5- DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis.

Images

	Immunohistochemistry of paraffin embedded human liver using NGAL (GB111134) at dilution of 1:1000 (400x lens)
	Immunohistochemistry of paraffin embedded human liver cancer using NGAL (GB111134) at dilution of 1:1000 (400x lens)
	Immunohistochemistry of paraffin embedded human lung using NGAL (GB111134) at dilution of 1:1000 (400x lens)
	Immunohistochemistry of paraffin embedded human lung cancer using NGAL (GB111134) at dilution of 1:1000 (400x lens)
	Immunofluorescence of paraffin embedded human colon using NGAL (GB111134) at dilution of 1:2000 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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