Anti -TANK/TRAF2 Rabbit pAb

價格：在線咨詢

貨號：

KT012185

產(chǎn)品規(guī)格：

Applications：

WB | IHC | IF

Species：

M,R/H

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	TANK/TRAF2 rabbit polyclonal antibody
Protein full name	TRAF family member-associated NF-kappa-B activator
Synonyms	TRAF-interacting protein, I-TRAF, Tank, Itraf
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse TRAF2
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm
Predicted MW.	51 kDa
Observed MW.	45 kDa
Uniprot ID	Q92844, P70347

Applications

Applications	Species	Dilution	Positive Sample
WB	Mouse, Rat	1: 500-1: 1000	brain, heart
IHC/IF	Human	1: 500-1: 1000	colon cancer, kidney, liver cancer, lung

Background

Acts as a regulator of TRAF function by maintaining them in a latent state. Overexpression inhibits TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May be involved in I-kappa-B-kinase (IKK) regulation; may function as an adapter for kinases such as TBK1 or IKBKE that can modulate IKK activity.

Images

	Western blot analysis of ITRAF (GB112338) at dilution of 1: 500
	Immunofluorescence of paraffin embedded human colon cancer using ITRAF (GB112338) at dilution of 1: 600 (400x lens)
	Immunofluorescence of paraffin embedded human kidney using ITRAF (GB112338) at dilution of 1: 600 (400x lens)
	Immunofluorescence of paraffin embedded human liver cancer using ITRAF (GB112338) at dilution of 1: 600 (400x lens)
	Immunofluorescence of paraffin embedded human lung using ITRAF (GB112338) at dilution of 1: 600 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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