Anti -BNIP3 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT012193

產(chǎn)品規(guī)格：

100ul

Applications：

Species：

H/M

品牌：

萬物

購買數(shù)量：

立即詢價(jià) 在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	BNIP3 rabbit polyclonal antibody
Protein full name	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
Synonyms	Bnip3, Nip3
Immunogen	Recombinant protein corresponding to Mouse BNIP3
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm
Uniprot ID	Q12983, O55003

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Human, Mouse	1: 1000-1: 2000	breast cancer, colon cancer, spleen, testis

Background

The BNIP3 is an apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway.

Images

	Immunohistochemistry of paraffin embedded human breast cancer using BNIP3 (GB111204) at dilution of 1:1000 (400x lens)
	Immunohistochemistry of paraffin embedded human colon cancer using BNIP3 (GB111204) at dilution of 1:1000 (400x lens)
	Immunohistochemistry of paraffin embedded mouse spleen using BNIP3 (GB111204) at dilution of 1:1000 (400x lens)
	Immunohistochemistry of paraffin embedded mouse testis using BNIP3 (GB111204) at dilution of 1:1000 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

凡合肥萬物生物科技有限公司銷售的產(chǎn)品均有嚴(yán)格的質(zhì)量保證。如發(fā)現(xiàn)產(chǎn)品存在包裝規(guī)格疑問，請于收貨之日起七日內(nèi)向我公司總部或當(dāng)?shù)剞k事處提出，并請保證該產(chǎn)品，以備本公司進(jìn)行核對(duì)檢驗(yàn)。如果發(fā)現(xiàn)有質(zhì)量問題，請于收貨后一月內(nèi)保留產(chǎn)品50%以上的量，以便本公司回收產(chǎn)品進(jìn)行質(zhì)檢，確認(rèn)產(chǎn)品質(zhì)量。如逾期，則視為已經(jīng)對(duì)本公司產(chǎn)品進(jìn)行驗(yàn)收。聲明：如發(fā)生產(chǎn)品索賠事宜，本公司僅在產(chǎn)品價(jià)格范圍內(nèi)酌情賠償，恕不接受超出產(chǎn)品價(jià)格范圍之賠償?？蛻粼谑褂眠^程中有任何技術(shù)問題可以撥打技術(shù)售后服務(wù)電話我們隨時(shí)給予解答。

合肥萬物生物科技有限公司

客服熱線：400-1016-218

QQ：355185756

地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國家大學(xué)科技園A401室